(00:19:40) Exercise Protects against Disease & Mortality The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. Find the obituary of Alberta Sinclair (1943 - 2021) from Chelmsford, MA. Health stuff a techbro/sis would find interesting. Correction and clarification: At time point 1:07:37, Dr. Sinclair says he takes 1 gram of Spermidine, but the active ingredient in the capsules is 1-2 milligrams. On this episode Sinclair goes in-depth on the process of aging and the techniques you can incorporate into your life that help you live a longer, healthier life, including optimizing your diet, the benefits of exercise, the role of a positive attitude, the importance of . Can you live a good life even when things are hard? They discuss the science behind. Season 1 will be 8 episodes in total and will launch on Wednesday, January 5, 2022. * Twitter To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com. Before we hear from Mollie Bell, a report from attorney Malik Shabazz on bringing Emmitt Tillls's accused killer to justice. (00:02:46) A Quick Primer on Free Radicals Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. * Twitter The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The latest science behind various beautifying therapies is highlighted, including newer interventions like low-level laser therapy and platelet-rich plasma injections.Thank you to our sponsors: Athletic Greens - https://athleticgreens.com/sinclair Levels - https://levels.link/sinclair InsideTracker - https://insidetracker.com/sinclairOur Patreon page: https://www.patreon.com/davidsinclairLifespan book: https://amzn.to/3sUqurTDr. (01:08:07) A Basic Protocol for Mimicking Adversity Nothing much happens; bedtime stories to help you sleep. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. Harnessing this knowledge, he was able to reverse this process, making mice younger, according to the study published in the journal Cell. The latest science behind various beautifying therapies is highlighted, including newer interventions like low-level laser . The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. (00:36:43) How to Measure your Biological Age Each episode offers tactical steps one can take to improve their wellbeing and achieve their goals from the world's top health experts in their field. A range of supplements. . What about work, wealth, purpose, service, or something else? (00:32:45) Bioavailability of NAD Boosters (0:25:11) Different Fasting Regimens 2: What to Eat and When to Eat for Longevity * Twitter (01:01:55) Options for Subscription and Support Tex, CAUTION: This conversation contains themes of an adult nature and references to sexual assault. (0:13:10) NAD+ is Elevated by a Low Energy State We cover food, fasting and fitness. We can all learn from unwelcome challenges and, more often than not, become better as a result of them. In each series, Marisa explores different topics to help you master your mind in order to master your life. Thank you to our sponsors: For Longevity | Episode 5. He's the co-host of the Lifespan Podcast. (01:08:51) Wrap-up and Next Weeks Episode: Interventions on the Cutting Edge Supplements and Highlight Points(00:09:54) Longevity Molecules Target the Survival Circuit(00:11:33) NAD Boosters(00:13:32) Nicotinamide Riboside(00:21:26) Nicotinamide Mononucleotide(00:29:22) NAD Intravenous Drips(00:32:45) Bioavailability of NAD Boosters(00:33:40) NAD and Cancer(00:35:33) Resveratrol(00:42:26) Red Wine and the French Paradox(0043:08) Fisetin and Quercetin(00:47:09) Rapamycin and Rapalogs(00:49:10) Spermidine(00:51:27) Metformin(01:00:27) Berberine(01:02:43) Dr. Sinclairs Protocol for Longevity Molecules(01:08:51) Wrap-up and Next Weeks Episode: Interventions on the Cutting Edge(01:09:52) Options for Subscription and SupportFor the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website.Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. In Episode 6 of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante discuss cosmetic aging and how to improve skin, nails, and hair. * Athletic Greens - https://athleticgreens.com/sinclair In Episode 6 of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante discuss cosmetic aging and how to improve skin, nails, and hair. (01:06:11) Targeting Aging Upstream David Sinclair Podcast He serves as the host of Lifespan on Scicomm Media. Chris Twitter: https://twitter.com/RealCSharp Chris Instagram: https://www.instagram.com/christopher Liberation Times Twitter: https://twitter.com/LiberationTimes Liberation Times Website: https://www.liberationtimes.com/ SUPPORT DISCLOSURE TEAM !, Paul Sinclair is recognised within the field of unexplained phenomena for his honest no nonsense approach to the subject. The Science of Keeping the Brain Healthy | Episode 7. Some of his key points this time: Eat less often. . Upcoming episodes will cover: why aging is a disease, the impact of dietary choices, fasting and exercise on aging, how various supplements and prescription drugs can protect against aging, why cosmetic aging occurs and how to combat it, the benefits and advancements of biotracking, and the future of age reversal. Early childhood 9:21 Are patient reviews good measures of a doctor? Different interventions aimed at preserving brain health are also discussed, including a plant-based diet, exercise, metformin, NAD boosters, and sufficient sleep.Thank you to our sponsors: Athletic Greens - https://athleticgreens.com/sinclair Levels - https://levels.link/sinclair InsideTracker - https://insidetracker.com/sinclairOur Patreon page: https://www.patreon.com/davidsinclairLifespan book: https://amzn.to/3sUqurTDr. Dr Mark Hyman has been a practicing medical doctor for several decades, he is the Head of Strategy and Innovation at the Cleveland Clinic Center for Functional Medicine and the author of, Are you scrolling on your phone constantly? * Twitter 9 episodes Join Dr. David Sinclair, Ph.D. in Lifespan, a popular health podcast that brings the cutting edge of aging and longevity science straight to you. Each week Ill be featuring inspirational stories and practical tips from some of my former guests. Recent pre-print paper - not yet peer reviewed - showing that mice treated with Yamanaka factors lived longer than the control group. (00:13:56) Peptide Supplementation and Regenerative Signaling Maybe its in social situations where youre surrounded by new people or work situations where its so easy to start spinning about everything from how youll be perceived to what happens if you stumble. (00:37:31) Exercise Recommendations Episode 6: The Science Of Looking Younger | Lifespan With Dr. David Sinclair. (00:00:00) Kicking Off Episode Four: Longevity Molecules If you don't like what Hollywood's execs tell you to like? In this weeks episode, Dr. David Sinclair and co-host Matthew LaPlante zero in on drugs and supplements that have been reported to combat aspects of aging. (00:07:11) Acknowledgement of Sponsors NMN, NR, Resveratrol, Metformin & Other Longevity Molecules | Episode 4. * Facebook This daily parade of the zombie children just cant bode well for the future. Exercise, Heat, Cold & Other Stressors for Longevity | Episode 3. Our Patreon page: https://www.patreon.com/davidsinclair As they discuss different adversity mimetics, they also explain how these interventions influence aging at the molecular and physiological levels. He was assigned to RAF Bentwaters in June of 1979 as a base policeman. To celebrate, I asked for questions from YouTube, Twitter, Locals and Instagram, so here's another 90 minutes of me trying to answer as many as possible. (00:25:05) Exosome Therapy (00:24:03) Vigorous Exercise, Hypoxia, the Electron Transport Chain The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. (00:10:09) Human Growth Hormone If you're new to the show, please check out episode #195 for Marco's full backstory and episode #271, which features a panel discussion Marco and I conducted before a live audience at the Miami . (1:07:23) Subscription and Support 89,911 views 1 year ago Welcome to Lifespan with Dr. David Sinclair. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. Top50 on Apple Podcast & Deezer ( Music Category ) in Spain Netherlands Russia Ukraine Bulgaria Hungary Romania & more Countries on the top 100 ( Source : itunes & Chartable.com ) Underground House Music DJ from Morocco LINKS: https://youtube.com/user/youness666b?sub_confirmation=1 https://podcasts.apple.com/fr/podcast/2021-house-tech-progressive-deep-defected-ibiza-uk/id1553828811 https://dj-tekness-morocco.business.site/ https://www.deezer.com/fr/show/2313652 @ DJ TEKNESS on Youtube Dee Dr. David Wensel interviews various guests who serve within the Medical Industry, Continuum of Care Industry, and Hospice Care Industry. The societal effects of therapies that successfully extend healthspan and/or lifespan are also considered. * Athletic Greens - https://athleticgreens.com/sinclair Season 1 will be 8 episodes in total and will launch on Wednesday, January 5, 2022. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. Joe Rogan Experience : aging, epigenome, genetics, healthspan, longevity, metformin, mtor, nad, nmn, rapamycin, resveratrol, sirtuin. 0:00 Intro 0:41 Story 2:34 Motivations 3:47 Building Doctify 8:25 Why do you have grit? For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. (00:21:55) mTOR & Rapamycin Lifespan book: https://amzn.to/3sUqurT My goal in creating this podcast is to discuss the science behind why we age and to share the newest research on what we can do to slow, stop and even reverse aging. Hear about the latest developments in aging research, lifestyle practices for longevity, exercise and nutrition science, and more. (00:09:54) Longevity Molecules Target the Survival Circuit For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website. (00:12:57) The Pinch Test, Epidermal Thinning, and Foot Ulcers Packed with inspiring stories of resilience, cutting-edge wellbeing revelations, and how each would make the world a happier place if made global dictator for the day. Special thanks to our research assistants, Adiv Johnson & Sarah Ryan. * Levels - https://levels.link/sinclair David Sinclair Social: Instagram Twitter FacebookMatthew LaPlante's Social: TwitterTo stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com.Timestamps:(00:00:00) Introducing Episode Seven: Aging of the Brain(00:04:39) Thanking the Sponsors(00:07:38) Ex-differentiation as a Driver of Aging(00:09:22) The Brain Ages Slowly(00:14:17) Cognitive Function and Plasticity(00:17:44) Three Longevity Pathways: mTOR, AMPK, and Sirtuins(00:23:26) Plant-based Diets and B-vitamins(00:28:32) Homocysteine, Plaque, and Vasculature(00:32:35) Fatty Acids(00:35:48) Physical Activity(00:39:14) Metformin(00:46:02) NAD Boosters(00:50:33) Increasing Blood Flor(00:53:20) Sleep(00:58:02) Overall Message: Keep your Brain Healthy(00:58:50) Next Weeks Episode and the Future of Medicine(01:01:21) Options for Subscription for SupportFor the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website.Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. 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